https://www.machform.com/requirements/ answers your question....? Requirements.....MySQL 4.1.10 or newer.
I want to update MySQL on my server from 5.6 to 10.3
I think you mean MariaDB 10. not MySQL. I can't see anything about MySQL 10; the current is MySQL 8......but typically I would say the most common stil in use is 5.x (5.6 or 5.7). I'd say stick with the commonly used, stable version.